{"_path":"/studies/44","_dir":"studies","_draft":false,"_partial":false,"_locale":"","id":"44","record_id":"44","name_study":"BioMD-Y  (biopsychosocial factors of major depression in youth)","dzpg_site":"München/Augsburg","description_study":"Purpose: BioMD-Y is a comprehensive biobank study of children and adolescents with major depression and their healthy peers in Germany, collecting a host of both biological and psychosocial information from the participants and their parents with the aim of exploring genetic and environmental risk and protective factors for major depression (MD) in children and adolescents.  Participants: Children and adolescents aged 8-18 years are recruited for either the clinical case group (MD, diagnosis of major depressive disorder) or the typically developing control group (TD, absence of any psychiatric condition).  Findings to date: To date, four publications on both genetic and environmental risk and resilience factors (including FKBP5, glucocorticoid receptor activation, polygenic risk scores, psychosocial and sociodemographic risk and resilience factors) have been published based on the BioMD-Y sample.  Future Plans: Data collection is currently scheduled to continue into 2026. Research questions will be further addressed using available measures.","title_pi":"Prof. Dr.","given_name_pi":"Gerd","family_name_pi":"Schulte-Körne","further_pi":"Ellen Greimel","contact_mail":"Gerd.Schulte-Koerne@med.uni-muenchen.de","contact_phone":"89440055918","paper":"Piechaczek, C. E., Greimel, E., Feldmann, L., Pehl, V., Allgaier, A.-K., Frey, M., Freisleder, F. J., Halldorsdottir, T., Binder, E. B., Ising, M., & Schulte-Körne, G. (2019). Interactions between FKBP5 variation and environmental stressors in adolescent Major Depression. Psychoneuroendocrinology, 106, 28-37. https://doi.org/https://doi.org/10.1016/j.psyneuen.2019.03.025    Piechaczek, C. E., Pehl, V., Feldmann, L., Haberstroh, S., Allgaier, A.-K., Freisleder, F. J., Schulte-Körne, G., & Greimel, E. (2020). Psychosocial stressors and protective factors for major depression in youth: evidence from a case-control study. Child and adolescent psychiatry and mental health, 14(1), 6. https://doi.org/10.1186/s13034-020-0312-1","website":"https://www.lmu-klinikum.de/kinder-und-jugendpsychiatrie/forschung/projekte/biomd-y/a79317962d6a2898","study_status":"Ongoing (II): Recruitment and data collection ongoing","type_intervention":["Non-interventional"],"type_specification_non_int":["Case-control","Family-based"],"type_specification_int":[],"setting":"Monocentric","setting_country":"Single","which_country":"Germany","participants":["General population","Patients with specific diseases"],"specific_diseases":["Mental, behavioural or neurodevelopmental disorders (06)"],"mental_disorders":["Mood disorders"],"somatic_disorders":[],"recruited":["General population","Hospital","Outpatient"],"n_participants_target":"-","n_participants_obtained":"~800","start_recruitment":"2009","min_age":"-","max_age":"18","data_sources":["Biological samples","Medical records","Interview","Questionnaire"],"data_sharing":"Undecided, it is not yet known if data will be made available","planned_follow_ups":"Yes","consent_recontact":"Yes","further_components":"Yes","biobank":{"biobank_material":["Blood"],"biobank_blood":["Serum","EDTA","PAXgene/Tempus"],"biobank_serum":["Other"],"biobank_serum_other":"The sample is collected and stored in the refridgerator at appropriate temperatures for future use/ extraction.","biobank_edta":["Other"],"biobank_edta_other":"The sample is collected and stored in the refridgerator at appropriate temperatures for future use/ extraction.","biobank_paxgene":["Other"],"biobank_paxgene_other":"The sample is collected and stored in the refridgerator at appropriate temperatures for future use/ extraction.","biobank_pbmc":[],"biobank_urin":[],"biobank_saliva":[]},"pi_full":"Prof. Dr. Gerd Schulte-Körne","_id":"content:studies:44.json","_type":"json","title":"44","_source":"content","_file":"studies/44.json","_stem":"studies/44","_extension":"json"}