{"_path":"/studies/67","_dir":"studies","_draft":false,"_partial":false,"_locale":"","id":"67","record_id":"67","name_study":"Analyse der Neurobiologie im Verlauf Affektiver Störungen - die Marburg Affective Disorder Cohort Studie (MACS) - FOR2107","dzpg_site":"Jena/Magdeburg/Halle","description_study":"Affective disorders, i.e. major depressive disorder (MDD) and bipolar disorder (BD), are complex and heterogeneous phenotypes. Genetic and environmental risk factors contribute to and interact with their etiology and the longitudinal course. The neurobiological correlates by which these predispositions exert their influence on brain structure and function are poorly understood. The aims of this Research Unit (FOR; DFG Forschergruppe) are to integrate clinical and neurobiological associations of genetic and environmental risk factors and their interaction involved in the etiology, onset and course of affective disorders.","title_pi":"Prof. Dr.","given_name_pi":"Udo","family_name_pi":"Dannlowski","contact_mail":"dannlow@uni-muenster.de","website":"https://for2107.de/","study_status":"Ongoing (II): Recruitment and data collection ongoing","type_intervention":["Non-interventional"],"type_specification_non_int":["Cohort","Longitudinal"],"type_specification_int":[],"setting":"Multicentric","n_sites":"2","setting_country":"Single","which_country":"Germany","participants":["General population","Patients with specific diseases"],"specific_diseases":["Mental, behavioural or neurodevelopmental disorders (06)"],"mental_disorders":["Schizophrenia or other primary psychotic disorders","Mood disorders","Anxiety or fear-related disorders"],"somatic_disorders":[],"recruited":["General population","Hospital","Outpatient"],"start_recruitment":"2015","min_age":"18","max_age":"65","data_sources":["Biological samples","Cognitive measurements","Imaging data","Interview","Questionnaire"],"data_sharing":"Undecided, it is not yet known if data will be made available","planned_follow_ups":"Yes","consent_recontact":"Yes","further_components":"Yes","biobank":{"biobank_material":["Blood","PBMC","Urin","Saliva","Other"],"biobank_material_other":"Stool, buccal swaps, strand of hair","biobank_blood":["Serum","EDTA","PAXgene/Tempus","Other"],"biobank_blood_other":"blood spots","biobank_serum":[],"biobank_edta":["clin-chem","Genetic","Epigenetic"],"biobank_paxgene":["Gene expression"],"biobank_pbmc":["iPSC","Epigenetic"],"biobank_urin":[],"biobank_saliva":[]},"pi_full":"Prof. Dr. Udo Dannlowski","_id":"content:studies:67.json","_type":"json","title":"67","_source":"content","_file":"studies/67.json","_stem":"studies/67","_extension":"json"}