Ongoing (II): Recruitment and data collection ongoing
The aim of this project is to investigate the neural mechanisms of action of ECT, especially with reference to (neuro-) cognitive functions and long-term treatment outcome. The design of this prospective, naturalistic case-control study includes 3 samples and 4 time points: A sample of depressed patients treated with ECT, a depressed control sample treated with psychotropic drugs only, and a healthy control subject group. Using structural and functional magnetic resonance imaging as well as a detailed neuropsychological test battery and clinical ratings, both direct and long-term effects of ECT will be examined at 4 time points: Before ECT treatment, after the ECT series, after 6 months, and after 12 months.
Redlich et al. (2016). Prediction of Individual Response to Electroconvulsive Therapy via Machine Learning on Structural Magnetic Resonance Imaging Data. JAMA Psychiatry https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2519363