Ongoing (II): Recruitment and data collection ongoing
Cardiovascular disease (CVD) is the leading cause of death worldwide with multiple forms of organ dysfunction, comorbidities, impaired health-related quality of life as well as frailty and dependency in the elderly. The greatest contribution to increased life expectancy between 1980 and 2002 is a reduction in age-specific mortality from cardiovascular diseases. Therefore, it is still necessary to collect and analyze data on development and progression of cardiovascular diseases in order to find new predictors for vascular events. The Berlin Longterm Observation of Vascular Events (BeLOVE) study is designed as a patient-based cohort study to provide a unique scientific structure and high quality data/biomaterial resource for a variety of studies on risk factors, interactions and causal mechanisms of different forms of CVD manifestations in a high-risk population. The objective of BeLOVE is to identify novel pathophysiological cross-disease mechanisms and treatment targets that determine both short and long-term outcome of high-risk patients with acute vascular disease. In the study patients with an acute index events due to acute cerebrovascular disorder, acute coronary syndrome, or acute heart failure, together with patients without an index event but a comparably increased risk to develop a cardiovascular event (one cohort - four disease entities).
currently in review
DRKS00023323