Analyse der Neurobiologie im Verlauf Affektiver Störungen - die Marburg Affective Disorder Cohort Studie (MACS) - FOR2107

ID

67

DZPG Site

Jena/Magdeburg/Halle
General Information
Status

Ongoing (II): Recruitment and data collection ongoing

Description

Affective disorders, i.e. major depressive disorder (MDD) and bipolar disorder (BD), are complex and heterogeneous phenotypes. Genetic and environmental risk factors contribute to and interact with their etiology and the longitudinal course. The neurobiological correlates by which these predispositions exert their influence on brain structure and function are poorly understood. The aims of this Research Unit (FOR; DFG Forschergruppe) are to integrate clinical and neurobiological associations of genetic and environmental risk factors and their interaction involved in the etiology, onset and course of affective disorders.

Contact
PI

Prof. Dr. Udo Dannlowski

Survey Results
Is it an interventional or non-interventional study?
  • Non-interventional
Specification of study type
  • Cohort
  • Longitudinal
Is it a mono- or multicentric study?

Multicentric

Number of sites

2

Is it a single or multi country study?

Single

Which country?

Germany

Who are participants?
  • General population
  • Patients with specific diseases
Which diseases? (ICD-11 classification)
  • Mental, behavioural or neurodevelopmental disorders (06)
Mental, behavioural or neurodevelopmental disorders (ICD-11 classification)
  • Schizophrenia or other primary psychotic disorders
  • Mood disorders
  • Anxiety or fear-related disorders
Recruitment setting
  • General population
  • Hospital
  • Outpatient
Start of recruitment

2015

Minimum age of participants

18

Maximum age of participants

65

Data sources for the study
  • Biological samples
  • Cognitive measurements
  • Imaging data
  • Interview
  • Questionnaire
Is it planned to share the data?

Undecided, it is not yet known if data will be made available

Are further follow-ups planned?

Yes

Is there consent to re-contact participants?

Yes

Is the implementation of further study components possible?

Yes

Biobank Module
Which material did you collect?
  • Blood
  • PBMC
  • Urin
  • Saliva
  • Other
Which other material did you collect?

Stool, buccal swaps, strand of hair

What type of blood collection tubes did you use?
  • Serum
  • EDTA
  • PAXgene/Tempus
  • Other
Which other type of blood collection tube did you use?

blood spots

Which type of data did you collect from EDTA?
  • clin-chem
  • Genetic
  • Epigenetic
Which data did you collect from PAXgene/Tempus?
  • Gene expression
Which type of data did you collect from PBMC?
  • iPSC
  • Epigenetic
View raw data